Global Health Security Implementation: Expanding the Evidence Base

Mixed methods research: expanding the evidence base.

74 Introduction ‘Mixed methods’ is a research approach whereby researchers collect and analyse both quantitative and qualitative data within the same study. 2 Growth of mixed methods research in nursing and healthcare has occurred at a time of internationally increasing complexity in healthcare delivery. Mixed methods research draws on potential strengths of both qualitative and quantitative me...

Expanding the evidence base for global recommendations on health systems: strengths and challenges of the OptimizeMNH guidance process

BACKGROUND In 2012, the World Health Organization (WHO) published recommendations on the use of optimization or "task-shifting" strategies for key, effective maternal and newborn interventions (the OptimizeMNH guidance). When making recommendations about complex health system interventions such as task-shifting, information about the feasibility and acceptability of interventions can be as impo...

The ventilator discontinuation process: an expanding evidence base.

The ventilator discontinuation process is an essential component of overall ventilator management. Undue delay leads to excess stay, iatrogenic lung injury, unnecessary sedation, and even higher mortality. On the other hand, premature withdrawal can lead to muscle fatigue, dangerous gas exchange impairment, loss of airway protection, and also a higher mortality. Continued ventilator dependence ...

The expanding evidence base for rTMS treatment of depression.

PURPOSE OF REVIEW Daily left prefrontal transcranial magnetic stimulation (TMS) for several weeks was first proposed as an acute treatment for depression in the early 1990s, and was Food and Drug Administration (FDA) approved in 2008. In the past year, several important studies have been published that extend our understanding of this novel treatment approach. RECENT FINDINGS The first round ...

Expanding the evidence base in an era of recovery.